Welcome to the ultimate guide on farming currency in Path of Exile 2 through The Trial of the Seamas, also known as Sanctum. Sanctum serves as the first Ascendancy Trial in Path of Exile 2 and, importantly, offers a lucrative way to accumulate wealth in the game. This guide focuses on the currency farming aspect of Sanctum. If you are a beginner looking for a general guide, I recommend checking out ELD.gg's guide (link in the description). With that said, let's dive into the details.

Should You Farm Sanctum?

The short answer: Yes! However, there are a few factors to consider before dedicating yourself to Sanctum farming:

1. Is Your Build Fast?

Sanctum requires traversing large areas quickly. Having a fast build will significantly improve your efficiency. Builds such as Stat Stacking Tempest Flurry, Queen of the Forest, or Temporales excel here. While it is possible to run Sanctum without a speed-focused build, doing so will lock you into specific strategies.

2. Is Your Build Strong?

Build strength only becomes relevant when facing Zarok, the final boss of Sanctum. While you don't need an exceptionally strong build to profit from Sanctum, more power provides flexibility in earning currency.

3. Can You Afford the Startup Cost?

Relic setups are crucial to maximizing profit in Sanctum. These setups can range from 1-5 Divines to 25+ Divines, depending on what you need to run Sanctum comfortably. Later in this guide, we will break down the most popular Relic setups.

How to Make Currency in Sanctum

There are three primary ways to generate Path of Exile 2 Currency in Sanctum:

1. Magic Relics

2. Unique Relics

3. Jewels

Let's explore each of these in detail.

Magic Relics

Magic Relics drop from monsters, chests, and merchants. Running a level 80 Ginbarer increases the odds of obtaining high-tier affixes on Magic Relics.

The key Magic Relics to prioritize include:

• Seals

• Urns

• Tapestries

• Mforas

Valuable Modifiers:

For Seals and Urns, look for the following:

• Increased Quantity of Relics (most important)

• Increased Maximum Life

• Increased Maximum Defenses

• Increased Maximum Honor

• Increased Movement Speed

For Tapestries and Mforas, look for:

• Additional Merchant Choices

• Reduced Merchant Prices

These modifiers are only valuable when paired together. If you find a relic with only one of these lines, consider using Annulment Orbs and Augmentation Orbs to roll the second modifier.

Additional profitable Magic Relics include:

• Seals and Urns with "Traps deal reduced damage"

• Seals and Urns with "+ meters to Dodge Roll distance"

• Seals and Urns with "Increased Quantity of Relics"

As your inventory fills up, carry a stack of Scrolls of Wisdom and Augmentation POE 2 Chaos Orbs to identify relics and discard junk items.

Unique Relics

Unique Relics drop exclusively from Zarok, the final boss of Sanctum. The most valuable Unique Relics include:

• The Desperate Alliance Vase Relic (~2.5 Divines, 15% drop rate)

• The Last Flame Incense Relic (~330 Divines, 0.5% drop rate)

Your Relic setup determines how many Unique Relics drop from Zarok, a topic we will cover in the Relic Strategies section.

Jewels

There are four main types of Jewels obtainable in Sanctum:

1. Standard Magic and Rare Jewels

2. Magic and Rare Time-Lost Jewels

3. Unique Grand Spectrum Jewels

4. Unique "Against the Darkness" Time-Lost Jewels

Where to Find Them:

• Standard Magic and Rare Jewels drop from mobs, chests, Silver, and Gold Royal Caches.

• Time-Lost Jewels drop from Time-Lost Caches.

• Grand Spectrum Jewels drop from Spectrum Caches.

• Against the Darkness Time-Lost Jewel drops from Zarok when using The Desperate Alliance Relic.

Valuable Jewels:

• Magic and Rare Jewels should be augmented and exalted, then stored in a dump tab for price checking.

• Grand Spectrum Jewel Values:

  • Rubies: Low value

  • Emeralds: ~0.5 Divine

  • Sapphires: ~9 Divines

• "Against the Darkness" Time-Lost Jewels (ATD):

  • Unidentified ATDs sell for 4-5 Divines.

  • Identified ATDs range from 90 Exalted to hundreds of Divines, depending on affixes.

  • Recommended: Sell Unidentified ATDs for consistent profit.

If you plan to identify ATDs, prioritize affixes such as:

• Spirit Attributes

• Gain Extra Damage

• Mana-Related Bonuses

Relic Strategies: Maximizing Profit

There is no one-size-fits-all Relic setup. Instead, follow this Relic Flowchart Strategy:

1. Prioritize Comfort

• Increase Honor, Movement Speed, and Damage

• Use Merchant Strategy for smoother runs

• Aim for autopilot-friendly setups

2. Stack Relic Quantity

• More Quantity of Relics = More Currency

• Optimize Seals, Urns, and Tapestries

3. Running The Desperate Alliance Relic

• Zarok is significantly harder when using this Relic

• Requires 4 vertical slots in your Relic setup

• Guarantees an ATD drop (profit of 2 Divines per run)

4. Sanctum: A High-Risk, High-Reward Currency Farm

Sanctum farming does not have a fixed Divines per Hour rate. The potential profit fluctuates greatly based on luck. For example:

• Early "Last Flame" drop → Hundreds of Divines per hour

• Consistent "Desperate Alliance" runs → Steady 2 Divines per run

Is Sanctum Worth It for Low Playtime Players?

Yes! While the odds of hitting the jackpot are low, a single Last Flame drop can kickstart your entire build.

Conclusion

Sanctum in Path of Exile 2 is an excellent method for currency generation or buy POE2 Currency, but it requires the right build, strategy, and Relic setup. By prioritizing comfort, stacking quantity, and using The Desperate Alliance Relic for guaranteed ATD drops, players can achieve consistent profits. However, for those seeking high-risk, high-reward farming, Sanctum also offers opportunities to strike gold with rare drops like The Last Flame.

Happy farming, Exiles!